DMPQ- What are yamanaka genes. Explain their role in our body.

Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse and human somatic cells, indicating that these factors regulate the developmental signaling network necessary for ES cell pluripotency. However, systemic analysis of the signaling pathways regulated by Yamanaka factors has not yet … Read more

DMPQ- . Write a short note on followings: (A) Performance budget (B) Revenue deficit (C) Quantitative Easing

(A) Performance budget Unlike the traditional line item budget, a performance budget reflects the  goal/objectives of the organization and spells out performance targets. These targets are sought to be achieved through a strategy(s). A Performance Budget gives an indication of how the funds spent are expected to give outputs and ultimately the outcomes. However, performance … Read more

DMPQ- Trace East India company’s response towards 1857 mutiny.

Company brought reinforcements from England, passed new laws so that the rebels could be convicted  with ease, and then moved into the storm centres of the revolt. Not only the police and military  personnel, but ordinary Britons were empowered to punish the Indians suspected of rebellion.  Rebellion had only one punishment – Death. Delhi was … Read more

DMPQ- Discuss the objectives and major features of PESA act of 1996.

The provisions of Part IX of the constitution relating to the Panchayats are not applicable to the Fifth Schedule areas. However, the Parliament may extend these provisions to such areas, subject to such exceptions and modifications as it may specify. Under this provision, the Parliament has enacted the “Provisions of the Panchayats (Extension to the … Read more

DMPQ- Briefly discuss the concept of Base erosion and profit shifting.

. It refers to the effect of tax avoidance strategies used by  multinational corporations on countries’ tax basis. The term was used for the first time by OECD. In an  increasingly interconnected world, national tax laws have not kept pace with global corporations, fluid  capital, and the digital economy, leaving gaps that can be exploited … Read more

DMPQ-. Discuss some of the important tools and technologies of biotechnology.

. Important tools which come under Biotechnology are as follows: Genetic engineering Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism. Traditionally, humans have manipulated genomes indirectly by controlling breeding and selecting offspring with desired traits. Genetic engineering involves the direct manipulation of one or … Read more

DMPQ-. World Health Organization plays an important role during the pandemic. Throw light on WHO’s roles and responsibilities amid Covid19 pandemic crisis.

Answer. The World Health Organization (WHO), the UN’s health agency, has played a crucial role in tackling the COVID-19 pandemic, ever since the first cases were identified in the Chinese city of Wuhan in December. Helping countries to prepare and respond The plan, which is updated as fresh information and data improve WHO’s understanding of … Read more